DNA Group 6
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International Lindsay* DNA Group 6

"Linzees of Boston, MA and Hants, England"

The defining term "Linzees of Boston, MA and Hants, England" is used in an attempt to establish a basic origin geography for the composite DNA Group 6.

The official web site for The Linzee Family Association of America, Inc. is  http://www.linzeefamilyassn.org/

The two (2) participants in DNA Group 6 match 26 out of 26 markers, as expected.

Click on DNA Data Spreadsheet to see the DNA marker values for the current participants of DNA Group 6.

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Since participants L0020 and L0021 are known first cousins, their Most Recent Common Ancestor (MRCA) actually occurred in 1867 (135 years ago) with the birth of their grandfather.

Anomaly Assessment

An anomaly is seen at marker number 10 (DYS394) for participants L0020 & L0021, where there are two values, 14 & 15.  Although it is not an unheard of occurrence, geneticists will say that it is a rare mutation.  The genetic conclusion is that a mutation occurred somewhere in this lineage which placed two copies of different lengths of the same DYS394 marker segment on the Y-chromosome of the males of this lineage.

A second anomaly occurred at marker number 15 (DYS447).  The most likely explanation for the "Null" anomaly initially found at marker DYS447, for participants L0020 & L0021, is that a mutation occurred, in the region of the Y-chromosome, flanking the actual "short tandem repeats" (STRs) of the marker DYS447 which prevented the primer from amplifying the site in the polymerase chain reaction (PCR).  According to current genetic statistics, this is a rare polymorphism but could be characteristic of this family lineage.

When participant L0021 upgraded to the expanded 43 markers, the Null reading at marker DYS447 was replaced with an allele of 31.  It is highly likely that L0020 has an allele of 31 at that marker also.

If you have information, accompanied by the appropriate citations, that demonstrate how these Linzee lineages of DNA Group 6 are connected with other known Linzee lineages, please contact Ron Lindsay

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Reference Notes

  1. Proper Analysis of DYS389-1 & DYS389-2 Marker Mutations.

In analyzing the marker values in the table representing this DNA Group, it is important to remember the following in your analysis of loci DYS389-1 and DYS389-2 matches and mismatches.

  1. The loci DYS389-1 and DYS389-2 are two legitimate lengths of DNA but move in tandem.
  2. DYS389-1 refers to the length of only one portion of the DYS389 marker.
  3. DYS389-2 refers to the total length of the DYS389 marker. Therefore, when there is a one step mutation at DYS389-1, it will also appear to be in DYS389-2.
  4. When comparing one individual to another, if the values for two individuals differ by one repeat at DYS389-1, that represents a one-step mismatch.
  5. If the values for the same two individuals differ also by one repeat at DYS389-2, then it should only be counted as one combined mutation for DYS389-1 & DYS389-2.
  6. If the marker values for two individuals differ by one repeat mismatch at DYS389-1 and a two repeat mismatch at DYS389-2, then it should be counted as two separate mismatches or mutations.
  7. There is another and potentially even more confusing situation that could occur at marker DYS389. If the marker values for two individuals differ by one repeat mismatch at DYS389-1 and then a perfect match at DYS389-2 for these same two individuals. This should be counted as two separate marker mismatches since the value mismatch at DYS389-1 was offset by a mutation in the opposite "direction" from the value found at DYS389-2 and appears to cancel out the mutation that occurred at DYS389-1.
  8. However, keep in mind there can be a mutation at DYS389-2 that will not affect the length found at DYS389-1.

End of Reference Notes

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Lindsay Code No.: L0020            
Surname of Participant: Linzee
Earliest Known Proven Progenitor: Thomas Linzee b. ca. 1627, d. November 19, 1680 Kingston, Portsea, Hants, England, married Elizabeth Hills.
  
Lindsay Code No.: L0021
Surname of Participant: Linzee
Earliest Known Proven Progenitor: Thomas Linzee b. ca. 1627, d. November 19, 1680 Kingston, Portsea, Hants, England, married Elizabeth Hills.
 
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* It has been established that the use of the Lindsay surname, throughout this web site, implies all the accepted different spellings of the surname found in the Orthography section.  
  • This web page was initially posted: October 14, 2002

  • This web page was last edited: March 16, 2010

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